美式高中课程专注于培养学生的创新精神，协作能力，正直和独立。我们鼓励学生在学校内外生活中的方方面面成为杰出领导者与优秀沟通者。在协和万源的美式高中，我们的学生们有机会逐渐成长为自信、有思想的，并且能直面挑战的未来领导者。iGEM是协和万源美式高中的一个特色项目，我们的iGEM队伍很荣幸能与麻省理工生物工程教授，同时也是BioBuilder课程项目的创办者娜塔莉库德尔博士合作交流，这次机会让我们的学生能与世界著名的科学家和教育家一起从学习者的角度、美式课程所提倡的公民参与度去改进教育教学。
A United States High School curriculumis centered around fostering innovation, collaboration, integrity and, independence. Our students are encouraged to be outstanding leaders and communicators in all aspectsof their lives – both inside and outside of the classroom. Throughout the USHS there are opportunities for our students to evolve into confident and thoughtful future leaders who can both effortlessly embrace and overcome the challenges they face. One of the most prestigious programs in our USHS – the international Genetically Engineered Machine (iGEM) team – is delighted to announce a collaborative endeavor with the famous MIT professor of bioengineering and BioBuilder educational foundation president – Dr. Natalie Kuldell. This opportunity for our students to work with such a celebrated individual is a testament to the approach to education, the learners’ attributes, and citizenship that the USHS program values.
娜塔莉库德尔博士 Dr. Natalie Kuldell
麻省理工生物工程学院教授
Instructor, MIT Department of Biological Engineering
BioBuilder 教育基金会主席
President, The BioBuilder Educational Foundation
化学康奈尔大学
博士细胞与分子生物学哈佛大学
A.B., Chemistry, CornellUniversity
Ph.D., Cell and Molecular Biology, Harvard University
我们热爱科学和社会研究的学生们从去年12月就已经着手开展制定项目计划，我们的队伍目的是构建工程化的微生物从而产出能大量使用在健康食品中的高价值欧米伽-3 脂肪酸。学生们的努力成果有望通过在今年10月在美国波士顿举办的2018 iGEM 大会发表生物工程化设计以及实验结果得以展现。
Students interested in scientific and social research have been working hard since December of last year on developing our project goal – which will aim to genetically engineer microbes with the goal of producing high value omege-3 fatty acids for the health food market. The team’s efforts will see them present our biodesign and experiment results in competition against universities from across the United States and around the world in the iGEM 2018 giant jamboree in Boston later this year.
除了科学研究项目，学生团队同样承担了具有教育意义的拓展项目，旨在促进高中生物课程及教学中工程设计思维及技能的使用。在2012年娜塔莉博士通过创办BioBuilder项目帮助高中教师们学习如何在课上教授新的合成生物学（工程生物学）和所需要的教学材料。当今世界迎合着的这个以基因操控的生物世纪影响着人们生活的方方面面，涉及能源燃料、食品、医学诊疗等。娜塔莉博士提到为了让未来一代积极为世界范围内的生命科学研究做出贡献或者为一个崭新的生物世纪做好准备，特别感谢工程师为改善人们生活所作的贡献。自从2015年来协和万源开始采用BioBuilder课程作为我们STEM教育内容的补充，我们学校投资建立了一个小型的专属的生物科技研究实验室，我们自豪地可以作为为数不多的中学生队伍参与这项赛事并与大学生研究团队同场竞技。
In addition to our scientific research and development, the team is also developing an educational outreach program designed to improve both the prevalence and quality of use of engineering and design skills in secondary school biology curriculum and classroom instruction. In 2012 Dr. Kuldell helped create the BioBuilder program which aimed to equip high school educators with the teaching know-how and resources required to implement the new science of synthetic biology (sometimes called engineering biology) in their classrooms. The world is currently in the age of biology where genetic manipulation now has the power to impact every individuals’ life in a multitude of ways, including our fuel, food and the rapeutics necessities. According to Dr. Kuldell, in order for the future generations to be active contributors in the world of life science research or indeed to be prepared for life in this new age of biology – “a deeper appreciation of what engineers do and how it relates to life is necessary”.
Since 2015 the USHS has adopted the BioBuilder curriculum to supplement our approach to STEM learning and have even invested in a small purpose-built Biotechnology research lab. This will be the second year we enter a team in iGEM and we can be proud to say we are only oneof fifty high schools world wide with the capabilities to perform such research for competition against university teams.
我们与身处波士顿的娜塔莉博士的第一次会议安排在一个周六的晚间，我们讨论了合成生物学或者工程生物学应用到中学教育中所面临的挑战，这也是她创办BioBuilder以及面向未来STEM教育的初衷。我们的学生认真的参与了这次有意义的对话，从中学生物课程以及从科学教育者的角度对于工程设计以及其教学方法的研讨有了深刻的见解。除了紧张的实验工作，我们团队给一些参与国际教育的科学老师分发了调查，从全球范围得到了80封的反馈，目前我们正在分析得到的早期数据，这些数据有利于制作免费的教育资源以提高生物教师在课堂上教授工程设计的能力。这些数据除了服务于我们团队自身的项目，同时我们也会和娜塔莉博士以及BioBuilder团队继续合作促进STEM教育在高中和初中生命科学教育的提高。娜塔莉博士也表示，希望加强该领域在中国的双语学校的普及和发展。
2018年度的iGEM 竞赛马上就要临近，感谢我们团队的努力工作，以及我们麻省理工的朋友们，还要感谢协和万源东西方交融的课程，我们非常自信学生们能取得成功。
Our first meeting with Dr. Kuldell, who resides in Boston USA, happened late one Saturday evening at WanYuan campus.Here we discussed the challenges facing synthetic or engineering biology education, her motivation for founding the BioBuilder foundation, and the future direction of global STEM education. Our students were deeply engaged in meaningful conversation with Dr. Kuldell and gained valuable insights into how to elucidate secondary school biology & science educators’ views on engineering design and how to perform a study into teaching methodologies. Currently our team, in addition to our strenuous lab work, have distributed a survey to international science educators about engineering design and teaching practices. To date, they have received over 80 respondents from across the globe and are currently analyzing the early data gathered. This data will be used to develop free educational resources for teachers designed to develop Biology teachers’ competences in teaching engineering design in particular. In addition to using this data for our own iGEM project we will continue to collaborate with Dr. Kuldell and the BioBuilder team to help improve STEM education in Biology high and middle schools. Dr. Kuldell has expressed her wishes for us to lead the implementation of synthetic biology education and BioBuilder to the Chinese bilingual schools sector.
iGEM 2018 is coming and thanks to ourstudent’s hard work, our friends in MIT and the USHS East meets West curriculum we are very confident our students will experience success.
来自与娜塔莉博士的访谈
协和万源：你做过一项研究关于教师在参与BioBuilder项目前后他们对于在学校核心课程中教授微生物学和生物技术的意愿，结果表明在接受项目培训后教师们普遍有自信心的提升，你觉得BioBuilder课程最大影响是什么？
From Interview with Dr. Natalie Kuldell
SUIS – One study that you conducted surveyed teachers on their attitudes to teaching microbiology and biotechnology in their core curriculum both pre- and post- BioBuilder training. The results showed a huge increase in teacher’s confidence with teaching these disciplines after training. What do you think is the biggest impact of the BioBuilder curriculum?
娜塔莉博士—最大的影响应该是教师们感到或者领会到有这么一种新的方式去教授生命科学。我觉得许多人远离生物是因为有太多需要记忆的内容，太多的术语，太多的越来越复杂的路径去学习。但是如果你用工程学思维去开展教学，它会帮助以某种方式组织信息，这让其变得有用和富有乐趣。举个例子学习基因的操纵子以及记住它的功能会变得更加简单，如果你能用得到它，或者把它看做一个检测环境污染的工具。这创设了学习情境，我想也是BioBuilder的最直接影响。但是我也感觉到它不仅仅能帮助学生和老师记起他们周围世界的信息，而是意识到你能做点什么让这个世界更美好，这就能吸引新的一代那些想为这个世界做点什么事情的人。这同样也能解放教师–如果你能放开想法，记忆内容，然后你能愉地开展教学工作和自我学习。我见过许多热爱学习，接纳 BioBuilder的教师蜕变得更好。
NK – The greatest impact has been that these teachers feel and appreciate that there is maybe a new approach to teach life science. I think many people leave Biology because there are so many things to memorize, so many words and so many pathways to learn it becomes overwhelming. But if you teach it through engineering it maybe helps organize the information in a way that is useful and personally engaging. For example, it is easier to learn about operons in genes and remember their function if you use them, or even think of them as an engineering tool to perhaps be used as a pollution detector in the environment. This adds context to the learning, I think this has perhaps been the most direct impact of BioBuilder. But I also feel that it has empowered both students and teachers. Empowered them to not just learn and recall information about the world around them but allows them to realize you can also do something with it, to you know, make the world a better place. I feel this is attractive to the next generation who are very motivated to do good in the world. It also liberates teachers – if you can let go of the idea that you need to know and remember everything then you can start to have fun teaching and learn yourself. I have seen that teachers also love to learn and to reengage them through BioBuilder has been wonderful.
娜塔莉库德尔—TEDxTalk—合成性的改变
Natalie Kuldell – TEDx Talk – Synthetizing Change
麻省理工教授娜塔莉博士使用最基本的材料解释到任何人都能在合成生物学中找到乐趣。但是如果学生、教师和成人爱好者能简单的给周围的生命世界重新编程，我们的星球最终会变成什么样呢？
MIT professor Natalie Kuldell explains that with just a rudimentary developer’s kit, anyone can engage in synthetic biology. But what will our planet eventually look like if students, teachers and adult amateurs can easily reprogram the living world around them?